From Path of the Vampire Wiki
Definition of Death
Dying as vampire simply refers to being sent to the Shadow Realm after you are killed. In order to be sent to the shadow realm, you must be drained of all blood followed by a critical wound - criticals from the sun, fae or NPCs do not count, so the critical must be dealt by another character, human or vampire.
You may also choose to 'kill' your character on the settings page.
Inside Shadow Realm
While you are in the Shadow Realm you will find spirits and other vampires to drain anima points from. To leave the Shadow Realm you must wait a certain amount of days. The duration you must stay is: less than level 5 - 3 days, less than level 10 - 5 days, above level 10 - 7 days. Once you have spent the required amount of days, you must then find an exit to return to the living world.
If you are having problems finding an exit, you can ask for help from those friends who are Fadewalkers. With their ability to enter the shadow realm at will, they can help you find an exit.
WARNING: Exits will move at random times in the shadow realm. So please do not be frustrated if an exit disappears.
To build up your anima before you leave the shadow realm, and lower your death woulds you have a couple of options. the first is to find spirits, bite them and receive one anima. The second is to push the $ button (same as robbing a character) and you will rob them of 1 anima. The third is to push the Attack button on a character. By doing this, you not only rob them of 1 anima but will increase one of their death wounds by 3 days. If you choose the third option, remember that this can be done to you and that the character might hold a grudge past death.
There are powers that can assist. Immortals and those who have shifted to the Immortal bridge can use Life Link which allows them to leave after gaining their anima without the need of an actual exit. Fadewalkers can also Enter the Shadow Realm at will, so long as they have not been sent there through death. However to get out of the Shadow Realm they must use a doorway, as the power is a one a way ticket. This allows them to share their anima with allies and lower their death wounds as need be. Fadewalkers can also use Shadow Crafting block squares, protecting themselves and others inside the square until the day change. After that the blocked square disappears. This power also allows them to edit the shadow realm at will.
Upon dying and entering the shadow realm (without powers) you will acquire a 'Death wound' that has a random stat loss of 2 points (3 for necromancers) for the first one. This first Death wound last for 3 months time and appears on your wounds page. The second death will cause you to lose 3 points (4 for necromancers) and last for 6 months. Third time, -4 (-5 for necro's) and 9 months. If you kill yourself, the death wound will have additional penalties in stat loss. To lessen the number of days on your death wound, you might want to consider staying inside of the Shadow realm longer to bite spirits, as this is the only way besides being on the Killer path and using the ability Healing Trance to lower the number of days it lasts.
WARNING Fadewalkers who have Curse Spirit can add 3 days while you are dead, or one day while you're alive. As mentioned above, any attack made on you will add 3 days and drain one anima point, steals by other vampires will only drain the single anima point from you.
Humans get rescued before they can die - which would normally happen when they are completely drained of blood. For more information on what this involves, read about Hospitalization.